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SARS-CoV-2 post-acute sequelae in previously hospitalised patients: systematic literature review and meta-analysis

Evidence type: Human RCT | Observational | Animal | In vitro | Regulatory Mechanism of Action As a copper chelator, GHK-Cu modulates over 4,000 human genes, upregulating those involved in tissue remodeling (e.g., collagen I, III) and downregulating pro-inflammatory pathways like NF-B

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A reduction in inhibition in the thalamus would therefore reduce inhibitory control of the thalamocortical relay cells, resulting in an increase in cortical excitability